MUTARS® Silver (silver coating)

Infection is one of the most severe complications of tumor arthroplasty, with rates reported in the literature between 5% and 35%, owing to long procedures, large incisions, and immunosuppression (chemotherapy and radiotherapy). The silver coating of MUTARS® components was developed to reduce this risk.

Silver, and in particular free silver ions, has a well-known broad-spectrum antimicrobial activity. The silver coating has been shown to reduce bacterial colonization of the implant surface. Only the non-articulating surfaces without direct bone contact are silver-coated.

MUTARS® Silver components have been CE-certified since 2007 and are considered a standard option in several major tumor centers across Europe; by the time of the brochure, more than 12,500 MUTARS® Silver implantations had been performed. Intraoperatively, wound irrigation with antiseptics containing H₂O₂, iodine, or heavy metals is not permitted (an oxidative effect that reduces the efficacy of the coating); NaCl, Lavasept®, or Prontosan® are recommended.

• Infection prophylaxis in tumor and revision arthroplasty with MUTARS® megaprostheses.
• Option for patients at increased risk of infection (long procedures, immunosuppression).